ConfuserEx supports .NET Framework from 2.0 - 4.5 and Mono (and other .NET platforms if enough request!). It supports most of the protections you’ll find in commerical protectors, and some more!

Symbol renaming
WPF/BAML renaming
Control flow obfuscation
Method reference hiding

Anti debuggers/profilers
Anti memory dumping
Anti tampering (method encryption)
Embedding dependency

Constant encryption
Resource encryption
Compressing output
Extensible plugin API